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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463f5b3980f8079da69c54cb2aee9b495601c5d65e2357c554987e8034f60062' 
  AND token = '9H2WGpIej2L1xzJ1+91RWRkKs47g4NI9hJIKmHcVyRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}