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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c7e006842be3120bfa98e032c2e5e3c972c7187a4bc3682e48c29fd857f000' 
  AND token = 'kDlmpYpnT9bG5voJ6j3sujU+lP/4htWFuFE3RNJOBUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}