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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57a1ce70fd7b06fa930b56575dddb76a7a964023e1f53e8f59d8de1c011a1b5' 
  AND token = 'Cxfc1Ji5DRnGDk+3GZPgbv1H3QxY9OitYvKFy2quqLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}