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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4fce01e42baf295e693e65282ccb43e8f67eb01920f0f3b80afd3c752d5c8c' 
  AND token = '9LOoaqcbsvzHWRvcJjm4A+lpvi1HI6oOCvdWI571TCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}