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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f99ac827a8ebddb69fee664f4a63b00fcbfed26dffddb043dfd1006981f70f' 
  AND token = 'F/K3kE8ckWlAjt8+q4LfM6Wr6pRWmdsPz4mT4iaNoY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}