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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5cdfb2123afe1a873785afaed261f2f95f05e4461b245406c83a8a6e70f2563' 
  AND token = 'pxL1d19Ok1s4P2nuh1M5rZWtbXoe3zb75Ow+BQYtoMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}