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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fa8614bdff160dd8f99234994767e2a5a8cb8dd39514cf9a6652e1bfbe8a41a' 
  AND token = 'Rm1Rw7W6I97PGK5s1i+pBmy/WT0pf9dPDIao4K8dL6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}