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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f008bbe3598a31023d94ee5adcd5ce8a6e5e10406860f7f4c853554bf360c9be' 
  AND token = 'VcHJbjsw7MUMJLfHHlnyJ6/kOJ2KCyex0AFtNslG3PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}