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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6579fdc9b334d0d97a8b3ba2a8780fcca0e7fc1005bf85d5ddbb17e032cee0' 
  AND token = '/gS1LzmZyi5R80263MmxPtyA5gS85JFcSkPDZNOC14I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}