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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab6c1748cb388f29bbff5cfe405736ce651a6a81dfa31cfacc859d17da436a2' 
  AND token = 'myAtyL+wQVC0pC3wZwxkojUdA9ztMSx34jm9rDmPjgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}