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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '855df69d57ee428a781a75f5f442470fd31fa47682bd7e53bea1585de0f6b7e4' 
  AND token = '9TAQpArUnGQXyfGm5Xzf1jdzmOoJy1kHrOgeeeCT9Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}