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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d2e247d4c02248d0b62e68d6856339926bc313f1925623d968af75568e11a6' 
  AND token = 'pFG4pkPJ1/GutL/ttQOyU1yeBFDnwkj/tFxGKUy3NcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}