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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4c99b2ea86d9c7fd3de52d4dee7502b4e9f726a0ef75f3a508c049d369042b' 
  AND token = 'iU9bGDKnYjnTI2wCdv0WdlCh7RtA4cHxjZ0qdSPEVAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}