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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5076d70e2517594968798d9bd6f7ad118937153fe140df64ae5e656c925936f1' 
  AND token = 'upsxePqgu228kQOPMYvZ2sWjXejym+hGrl2pWF9rP2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}