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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8871376d44aae7a45e249d3dbab1659735b52aa5b4f80817458362479b2185' 
  AND token = 'sAC4HKkSSX5fvX3FhqkpHQ3cS98WdXuaGAIl1aT5dxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}