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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18daf7ec88bc1b7e761d192ab9e2c29dec9e2fe4466df65afaa7032262a1b9b' 
  AND token = 'NPkxRQgrUci2q2hc06JyaFsjXdYHqoCkhgTh0aHx7B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}