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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665b8b1160d6cfab83dbfc22ff5e0c495e903343bdda381420aa9e0a603f98bb' 
  AND token = '7V0Z6TcHUJ2J/XKAGwGx+DqK2o32Ntw2Lz/XzAkUsaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}