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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7879e0f47fed6714a9fa7231e079bf07caacce8e7a7aff51125e7c70b952970b' 
  AND token = 'BhE3rhm1nGZpTFBmHCg+0sEKHJPjF1nFryzv1xW1TpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}