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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c2fa827a0d0991b00db11773a6f4d87d8621c7a91d7de1b5c993ca91ae47a9' 
  AND token = 'aJ38BMrcBlLf1ovQcIKPQUyYfpOYlI6ev0WO3EdtkRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}