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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2393675e00379413abc91d41835f50bc23c91913b0571fe44dedad76ebe0890' 
  AND token = 'r6tUCEY2mC0NA8vmS/ACV3kZdFne1RLYmKSDcMu8PmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}