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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e7cbc0b261c190437c2f6fdb0d2d7cbd7c25c251d5c75f54125f0c4968b523' 
  AND token = 'rpBmCjkLv36MuND3jcgTUIbkm+YjbveceCHsx4cu0uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}