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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48f4e562288a11a0528476d673856ca1725bccc8a44221f9c9e7e9ebfca14b2' 
  AND token = 'CZIFA0wuS2URX1eiHJ+WQqxpsL2EnPyTyofXL6/6XjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}