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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67b7f2aa9078ed098249ccdf41d7d3dfc44e59e1bc50b15a571e5ef6b1c21080' 
  AND token = 'P+5U+ldRdnxuYiqTQK1aBl0m9DSIM9NCIAGXFwWeP8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}