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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1536f3b90ea0206c889e4974c964d0ca1dbea05d76c55aea4548cee541bde4a2' 
  AND token = '1MC8oRxzOUw2ZxRHiE9BRgIMjoSoDvBy4B2Ys+6nt8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}