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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0443b662c47c4908dd925fc0092cc0de3d7cbc0b55fb13dc47adb24e5f5619a8' 
  AND token = 'rOF43TYntfsTtcDFCY1Y1dqLL/b1GiB+/GAoRpiw/0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}