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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1791b77acc904a1345c6a645fd376cac086d80415e7bf6336ef16a21f40c6f' 
  AND token = 'FdAnesonbPgCzxnvQsAdFS6q1mUYKFNsHCgjeFW3ZOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}