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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6644981086df50ede45adb6111847b4062564114b239aa4830e2d45cd0cb0d7' 
  AND token = 'En3Bff49AF8dDDWvdNY+MR31dKhY6zk/0A95GUI6cHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}