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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306e07b5b5d8ba28076a96f22ea545a45a202872e5030e35b54fd04456afa322' 
  AND token = 'UqORtWdoNGHGPIOWt98jCa9ManeMvvyqDy+mTpvH1F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}