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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc8e4215cf7fbace3f06dc27574bb26a90402385412e54d78b7d100048d15295' 
  AND token = 'vmO2taY36yy0hmsKdnF5/JNte4xlQX7SuiLLRqOxggk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}