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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4697deb2cdd63197df4461ed14ec08079aa0aa12ee8d9bac78eec296f6637409' 
  AND token = '1+1d5MsgdxlJ8mPt1xulAVHu0/y6L9WaiT5JqYirpng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}