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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0fae43121b22144aa0d4a70f2c20391c88de1e0ab27b88f483b4174e8029e4' 
  AND token = 'OsTk/aMy4uTtGVGsZrY13jtbkx9On1DODml/Felk7A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}