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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5951f3cb23507d302bef4b0f948e296563413dfad98b7c955e63c7d648997c5e' 
  AND token = 'K5v1/KYfE6sDQmKy63sKevuA0DkwsRK29tTwMa1cyY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}