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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b8eafcacc7515ec80bf74583c3d6946cb5155c624a7a04e44cb40a2238cf00' 
  AND token = 'VtB8Z8jLHUkKRRF/CaMp90LgoFV836sMN3o0Iqum1vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}