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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '409c1f74da91232b251699076ce6c4fdfc67ce511985989df3553b1d17bdb555' 
  AND token = '4bzshU7XEDbjq+42zRv3XAnAOxKcpYtDMITsSlNrsCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}