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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6fb47d0a7008936ad979ca181d06de3cd1196b3a3421448a9cafaa7a458865' 
  AND token = '0h0+zVY4B/iFQP08S+Dk00KXBTsd4kHim6OPmflHHz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}