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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226dc526e989f326f967b0850cb6ceb25d01b49f47e104d105a755942d6cb715' 
  AND token = 'GlXT5JUEQB/EZIlmB1HGxI7AT2AwsU+rGM1Fuyk9Ncs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}