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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11bc7989ceb3f468e84cae6f21f3eb6bcf312f74bda4261a041ade94b1bb772a' 
  AND token = 'LmBj4ZBBT8twQtOYKAEBnzxMMyeGJMTSOgCvqMCM6s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}