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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443532fb62e6bb5cdee9a5a86354d694280f55b2cc80d92fb43ff1322023b07f' 
  AND token = '8T4+jVXikr6o0rglaizajPSRZ3WLFU3tUrFasruku3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}