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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '172ece1818683984043827b2d75555be691c0a37839cf7833b83c8fd7c8ff7db' 
  AND token = 'FCoGu7ZqnsrwGUZ6CDkTbtmPLD/njjCSUTnj7WWI6fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}