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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfebf39f921e9d15f1ba663b002a96720f829255660574f5ad30d427c5362c08' 
  AND token = 'TDulPq/Ls1lEyOxya5BLn9iQgQBEKm0nYPBb2hxiUVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}