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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288d0a2334a0f48ce86fc63f63c108d861805a556c6c5623d34a5d0f696bb7bf' 
  AND token = '3EL6XAOEfSV8MWw4Lc59lb1JVEwwbG67Wuunr0DMoSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}