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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52d77541f7a9ca3ee8ea10076a3b1a763e5075d658a72754ca95c81cc48e3d5' 
  AND token = 'SDe66VlAuUFPJ50kX42Tcrvs4kliXBYZD0Jpf9v3GpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}