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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4e1af59ce106b27323cfc00beb84ea0bf288f3edceda55e09f5613bd5ce2f0' 
  AND token = 'TxLAtJH9yliA/8dGdpkKM+U+yIISaWmJVoD8xs0kTZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}