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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735622f980b1c692c0c42b1490a31c03df2b5eb0e8d2499a36ac84eeed2321d4' 
  AND token = 'koPTSHR+F/cqC1Rp9EzIb+eT8utDE/FtG78pdy9YJl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}