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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd16a69e0a88969c86b2c481604fb99ced740248601f58c0d427b858cbc1142' 
  AND token = 'TlPyhun6Wo3Px4EP/IteZA5FkbfPiB66XmkCN8WIi5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}