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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5579b46ab609418f9ecb8cc4f89f69b7878c7d8c541abe85002d3e6aec03d0' 
  AND token = '50MmM47hlHFhaMwYmJegCmPvaK4lTPoOpaTAq+uCzZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}