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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fad83b75cfb1fe9f6c2708b213bccf497381baa998fbbc3cb95a08bccda750b' 
  AND token = '0x1uHf2O3ICFJCXxWQhpxIB3YEswrc9E37GcG8BcNTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}