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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a9bd9de78e1a0a988340b042a8c426ace1a00f6e7161328dd1d10e80b0af2a' 
  AND token = '1/3N8LR814Gsaj3tSrFdOm5r2u1xaOk2e1k8lh7ThvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}