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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de2b1337d9f90153e185c973c413a7311d77c22b3ad21f3da0b290313bf9b27' 
  AND token = 'L3MRRqkXH4PdOVKth6+1QVaYS1T/zNnz88cuPDS1G8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}