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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cefa73b1f4b691f5ac11e3812b45d0e46db2c44ff296f4e5fa3271ce0ec3e36' 
  AND token = 'E1KfMnpEBCQMjiuIJ0ffhqJTf2MrR41LRQVl9CLkhxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}